图邦病毒(學名:Tupanvirus)是擬菌病毒科的一個屬,包括两种巨病毒:深海图邦病毒(Tupanvirus deep ocean)和盐湖图邦病毒(Tupanvirus soda lake),皆以變形蟲為天然宿主,其名稱图邦(Tupan)一词来源于瓜拉尼语的Tupã(瓜拉尼神话中的创世主神、雷神)。图邦病毒是已知唯一一類具有20种胺基酸之氨醯-tRNA合成酶基因的病毒。[1][2][3]
图邦病毒的病毒体可达1.2微米长,其衣壳与拟菌病毒的大小和结构类似(约450纳米),此外图邦病毒体还具有一个长550纳米、直径450纳米的柱状尾部,与衣壳底部相连。由于尾部大小的差别,有的图邦病毒可达2.3微米。图邦病毒的基因组為長约1.5Mb的双链DNA,用于编码1276-1425种蛋白質,其基因组包含许多參與细胞生物反應的编码基因[1]。
图邦病毒是已知病毒中,基因組裡具有最完整的轉译元件者,包括多達70種tRNA、20種氨醯-tRNA合成酶、11種轉譯所需的蛋白質、以及多種可修飾tRNA、mRNA與核糖體蛋白的酵素,還具有與18s核糖體RNA高度相似的序列[4]。
- ^ 1.0 1.1 Garisto, Dan. These giant viruses have more protein-making gear than any known virus. 2018-02-27 [2020-02-10]. (原始内容存档于2018-07-01).
- ^ Abrahão, Jônatas; Silva, Lorena; Silva, Ludmila Santos; Khalil, Jacques Yaacoub Bou; Rodrigues, Rodrigo; Arantes, Thalita; Assis, Felipe; Boratto, Paulo; Andrade, Miguel; Kroon, Erna Geessien; Ribeiro, Bergmann; Bergier, Ivan; Seligmann, Herve; Ghigo, Eric; Colson, Philippe; Levasseur, Anthony; Kroemer, Guido; Raoult, Didier; Scola, Bernard La. Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere. Nature Communications. 2018-02-27, 9 (1): 749. Bibcode:2018NatCo...9..749A. PMC 5829246
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- ^ Schulz, Frederik; Yutin, Natalya; Ivanova, Natalia N.; Ortega, Davi R.; Lee, Tae Kwon; Vierheilig, Julia; Daims, Holger; Horn, Matthias; Wagner, Michael; Jensen, Grant J.; Kyrpides, Nikos C.; Koonin, Eugene V.; Woyke, Tanja. Giant viruses with an expanded complement of translation system components (PDF). Science. 2017-04-07, 356 (6333): 82–85 [2020-02-10]. Bibcode:2017Sci...356...82S. PMID 28386012. doi:10.1126/science.aal4657. (原始内容存档 (PDF)于2018-07-24).
- ^ Abrahão, Jônatas; Silva, Lorena; Silva, Ludmila Santos; Khalil, Jacques Yaacoub Bou; Rodrigues, Rodrigo; Arantes, Thalita; Assis, Felipe; Boratto, Paulo; Andrade, Miguel. Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere. Nature Communications. 2018-02-27, 9 (1): 1–12 [2020-02-10]. ISSN 2041-1723. doi:10.1038/s41467-018-03168-1. (原始内容存档于2019-11-03) (英语).