1-羥基菲
外觀
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1-羥基菲 | |
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IUPAC名 Phenanthren-1-ol 菲-1-酚 | |
別名 | 1-菲酚 1-菲醇 1-羥基菲 1-羥菲 |
識別 | |
CAS編號 | 2433-56-9 ![]() |
PubChem | 98490 |
ChemSpider | 88945 |
SMILES |
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性質 | |
化學式 | C14H10O |
摩爾質量 | 194.23 g·mol⁻¹ |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
1-羥基菲(英語:1-Hydroxyphenanthrene)或叫1-羥菲,是一種菲酚和菲的人體代謝物,可以在暴露於多環芳香烴的人的尿液中檢測到。[1]
它還可以用作海洋魚膽汁中多環芳香烴污染的標記物。[2]
在菲生物降解的情況下,模型真菌雅致小克銀漢霉產生1-羥基菲(菲1-O-β-葡萄糖)的糖苷共軛物。[3]
與吸煙的關係
[編輯]對於2-、3-和4-羥基菲和1-羥基芘,發現了與每天吸食的香煙有關的高度顯着差異和劑量反應關係,但對於1-羥基菲則沒有。[4]
參考資料
[編輯]- ^ PAH metabolites (1-hydroxyphenanthrene, 4-hydroxyphenanthrene, 9-hydroxyphenanthrene, 1-hydroxypyrene). The MAK Collection for Occupational Health and Safety, Biomonitoring Methods, Vol. 6 (article (頁面存檔備份,存於互聯網檔案館))
- ^ PAH Metabolites in Bile Fluids of Dab (Limanda limanda) and Flounder (Platichthys flesus): Spatial Distribution and Seasonal Changes. Ulrike Kammann, Environmental Science and Pollution Research - International, March 2007, Volume 14, Issue 2, pages 102-108, doi:10.1065/espr2006.05.308
- ^ Cerniglia, C. E.; Campbell, W. L.; Freeman, J. P.; Evans, F. E. Identification of a novel metabolite in phenanthrene metabolism by the fungus Cunninghamella elegans. Applied and Environmental Microbiology. 1989, 55 (9): 2275–2279. PMC 203068
. PMID 2802607. doi:10.1128/AEM.55.9.2275-2279.1989.
- ^ Urinary monohydroxylated phenanthrenes and hydroxypyrene – the effects of smoking habits and changes induced by smoking on monooxygenase-mediated metabolism. Heudorf U and Angerer J, International Archives of Occupational and Environmental Health, April 2001, Volume 74, Issue 3, pages 177-183, doi:10.1007/s004200000215