16BO133病毒
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16BO133病毒![]() | |
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病毒分類 ![]() | |
(未分级): | 病毒 Virus |
域: | 核糖病毒域 Riboviria |
界: | 正核糖病毒界 Orthornavirae |
门: | 小核糖病毒门 Pisuviricota |
纲: | 小南嵌套病毒纲 Pisoniviricetes |
目: | 套式病毒目 Nidovirales |
科: | 冠状病毒科 Coronaviridae |
属: | 乙型冠狀病毒屬 Betacoronavirus |
亚属: | SARS乙型冠状病毒亚属 Sarbecovirus |
种: | 嚴重急性呼吸系統綜合症相關冠狀病毒 SARSr-CoV
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毒株: | 16BO133病毒 16BO133
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16BO133病毒是嚴重急性呼吸系統綜合症相關冠狀病毒(SARSr-CoV)的一個病毒株,在韓國的馬鐵菊頭蝠中發現,於2019年發表,其基因組被完整定序,是首個被完整定序的韓國SARSr-CoV病毒株,在SARSr-CoV中屬於SARS-CoV相關病毒,與其基因組序列相似度為82.8%。
發現
[编辑]16BO133病毒於2016年在韓國馬鐵菊頭蝠的口腔樣本中被發現,此病毒株的基因組長29075nt。在SARSr-CoV中,16BO133和2016年發表、自中國吉林馬鐵菊頭蝠中發現的JTMC15病毒最為接近,基因組核酸序列相似度為98.3%,與其他SARSr-CoV相較之下,這兩個病毒株因爲ORF7b末端的框移突變而喪失了ORF8[1][2]。16BO133病毒和SARS-CoV的基因組核酸序列相似度則為82.8%[3]。
過去雖有其他SARSr-CoV病毒株在韓國被發現(B15-21病毒等),但皆無完整序列定序[4],16BO133病毒是首個被完整定序的韓國SARSr-CoV病毒株[1]。
演化樹
[编辑]截至2021年1月[update],SARS-CoV與相關病毒株的系統發生樹:
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SARS-CoV-2 79 % | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
參考文獻
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- ^ He, Biao; Zhang, Yuzhen; Xu, Lin; Yang, Weihong; Yang, Fanli; Feng, Yun; Xia, Lele; Zhou, Jihua; Zhen, Weibin; Feng, Ye; Guo, Huancheng. Perlman, S. , 编. Identification of Diverse Alphacoronaviruses and Genomic Characterization of a Novel Severe Acute Respiratory Syndrome-Like Coronavirus from Bats in China. Journal of Virology. 2014-06-15, 88 (12). ISSN 0022-538X. PMC 4054348
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- ^ 8.0 8.1 Lau, Susanna K. P.; Feng, Yun; Chen, Honglin; Luk, Hayes K. H.; Yang, Wei-Hong; Li, Kenneth S. M.; Zhang, Yu-Zhen; Huang, Yi; Song, Zhi-Zhong; Chow, Wang-Ngai; Fan, Rachel Y. Y. Perlman, S. , 编. Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination. Journal of Virology. 2015-10-15, 89 (20). ISSN 0022-538X. PMC 4580176
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